Top 5 Reasons Why Acetaminophen is The 'Most Common Cause Of Liver Injury In Canada

Date : 19 Jul 2022


Acetaminophen was authorized for use by the FDA in 1951. Although it has a long history of widespread use, experts are not sure how acetaminophen works in the body. It is believed to reduce the number of chemicals that cause inflammation and swelling in the brain. It lowers the sensation of pain by raising the pain threshold. The side of the brain that regulates heat is affected by acetaminophen, as it is said to lower body temperature is too high. Generally, acetaminophen is a well-tolerated drug, so few side effects are present often experienced. Common side effects of the drug include nausea, stomach pain, loss of appetite, headache, yellowing of the skin or eyes, and dark. While most people do not have problems with acetaminophen when taken as directed, it is possible to experience severe adverse reactions. An allergic reaction identified by difficulty breathing, hives, severe itching, peeling, blistering, and swelling of the face, lips, throat, or tongue is all reasons for immediate medical attention.

It is possible to experience acetaminophen toxicity in the form of severe liver damage when too much of the drug is consumed. Whether intentionally or by accident, an overdose of acetaminophen needs immediate attention to prevent further damage to the body. Symptoms of liver damage include:

  • Yellow skin or eyes,

  • Stomach ache,

  • Nausea and vomiting,

  • Loss of appetite,

  • Tiredness,

  • Excessive sweating,

  • Darkness on feces,

  • Pale skin color,

  • Unusual bruising, and 

  • Abnormal bleeding.

Further complications may arise with acetaminophen as it interacts with other drugs. Antibiotics, antifungals, sulfa drugs, nonsteroidal anti-inflammatory drugs, birth control pills, and drugs to treat high blood pressure, cancer, high cholesterol, arthritis, HIV and AIDS, seizures, and mental disorders can all make acetaminophen affected. But if you take it under a healthcare prescription, it is beneficial for your health. You can easily buy acetaminophen from the Alliance Easy rx website at respectively affordable prices compared to other sites. It is the best place to buy any medication and research chemicals without a prescription online to get an order on your door. 

Causes Of Liver Injury By Acetaminophen 

Acetaminophen is considered safe when used under the direction of the doctor. The cause of liver damage is possible:

  • Take the product for longer than recommended

  • Take more than enough of the prescribed daily dose

While the liver breaks down acetaminophen, it can build up and become toxic if you take too much. Acetaminophen accumulation can cause a type of liver injury called hepatitis-induced hepatitis. When it is hard enough, it can affect the way your liver works or even cause your liver to stop working. Hepatitis may be caused by alcohol or other liver diseases, including viruses such as hepatitis A, B, or C. If you have liver disease, you should consult your doctor before taking acetaminophen.

 But if you take the appropriate amount of doses under the doctor, you do not worry about your liver health. You can easily uy online acetaminophen from the Alliance Easy rx website at respectively affordable prices compared to other stores. The risk of liver damage have with acetaminophen may be higher if you:

  • Have liver disease.

  • Drink a lot of alcoholic drinks every day, even if you follow the recommended dosage range.

  • The high amount you can safely take may be less than the product labeled price.

  • Use acetaminophen for a long time, even in recommended doses.

All medications, both prescription and over-the-counter, have risks and benefits. Read the labels carefully of any medicines, those you take each time you start using them. Look at the top five reasons for acetaminophen that are causes of liver injury in Canada. 

  • Chronic alcohol use with acetaminophen use may increase the risk of liver damage and stomach bleeding. The substance of matter that increases stress on the kidneys and liver poses significant health hazards, especially when combined with acetaminophen. The Food and Drug Administration prescribed consuming no more than three alcoholic beverages a day if you plan to use acetaminophen.

  • Acetaminophen poisoning, also known as acetaminophen overdose, is a well-known cause of acute liver failure. A person may intentionally take more medicine than is safe, or they may accidentally consume too much acetaminophen, which can happen when taking several cold medicines containing acetaminophen.

  • Whether the symptoms and treatment of liver damage are similar, supportive measures, such as IV fluids and anti-nausea medications, can help someone recover from acetaminophen poisoning. Most people recover from the effects of an acetaminophen overdose. In rare cases, however, toxicity may progress to liver failure, which would require a liver transplant. Death can also occur after an acetaminophen overdose if not treated promptly.

  • The most commonly used drug in the United States, acetaminophen, is hard for many people to imagine as a substance of abuse. Used for the daily treatment of common aches and pains, the drug's over-the-counter accessibility makes it a prime candidate for self-medication. If you use it as the direction of a doctor, acetaminophen is safe and unlikely to cause adverse side effects when acetaminophen toxicity can quickly lead to liver damage when misused or overused.

  • Liver damage associated with acetaminophen use sends thousands of Canadians to the hospital every year. The side effects of acetaminophen use do not usually last long, but if not treated properly, it can lead to serving liver damage and even death.

Safely Use Of Acetaminophen.

Acetaminophen is safe and effective when you take it as a director of healthcare. You easily order online acetaminophen from the Alliance Easy rx website at respectively affordable prices compared to other sites. The amount of acetaminophen taken in a day should not exceed 4,000 milligrams from all sources:  Adults, and children 12 years and older. Over 24 hours, this is equal to:

  • 8 Extra Strength tablets (each tablet contains 500 mg)

  • 12 regular-strength tablets (each tablet contains 325 mg)

The maximum amount of acetaminophen that you can take in one day is low for children under 12. Weight and age-based dosing instructions are provided with children's acetaminophen products. If you are taking a product containing acetaminophen, you should do the following.

  • Read the product label and follow the directions.

  • Follow guidelines on how much to take, how often to take, and when to stop.

  • Keep track of how much and when you have taken it.

  • Avoid taking more than one medication of acetaminophen at the same time.

  • If you are required to take more than 1 product containing acetaminophen, be aware of the maximum recommended daily dose.

  • Adults, children 12 years above and older should not exceed 4,000 mg of acetaminophen from all products.

Many medicines contain acetaminophen. You should necessarily consult your pharmacist or health care provider if you have doubted:

  • You are not ensured if a product contains acetaminophen

  • You're not sure how much you're taking

  • You have questions about the risk factors associated with acetaminophen

  • If you think you have taken enough acetaminophen, you should immediately call your provincial poison control center.

Overdose Of Acetaminophen Main Causes Of Liver Injury In Canada 

You can easily buy online Tylenol acetaminophen from the Alliance EasyRx website at respectively affordable prices compared to other stores. But it is important to take it in prescribed doses, not enough more. Overdose means more than enough. Taking too enough acetaminophen, either by accident or on purpose, is called an overdose. With acetaminophen, symptoms do not appear until several hours after overdose. You could have liver damage, and you do not know it. Acetaminophen overdose in Canada, the USA, and many other developed countries is a leading cause of liver failure. The word acute in this context means that damage occurs rapidly over hours or days.

In comparison, damage from chronic liver failure occurs over many years. There are approximately 5000 hospitalizations in Canada each year due to acetaminophen overdose. About 700 or 20% of these were reported as accidental or unintentional overdoses. Liver injuries, including severe liver damage, develop in approximately 6% of patients hospitalized for an overdose. This means that the liver suddenly stops working, which can happen:

  • Need liver transplant

  • Cause of death

  • Behaviours that most commonly lead to accidental overdose include:

  • Next dose very soon

  • More than the recommended dosage at one time

  • Too many people underestimate the risk of doing so

  • Two or more types of medicines contain acetaminophen at the same time. For example, pain relievers with cold and flu medicine.


Every year many people use acetaminophen in Canada and the USA for the treatment of flu, cold, pain, etc. It is best to take it in appropriate quantity. But overdose of acetaminophen is harmful to your health, and it is also the leading cause of liver failure in Canada. Taking acetaminophen drugs under the guidance of doctors and pharmacists is good for your health. You can easily buy online acetaminophen from the Alliance EasyRx website at respectively affordable prices compared to other stores because it is the best place to buy any medication and research chemicals.